Royal Air Force Typhoon FGR4s have conducted a mission with French aircraft in a coordinated attack targeting an underground arms cache in Syrian territory used by the Daesh militant organization, according to the UK's MoD.
The facility, located using reconnaissance, was believed to be containing munitions and bombs, the release indicated, and was positioned in mountains just north of the ancient city of Palmyra in the heart of Syria.
"Our fighter planes employed Paveway IV guided bombs to target a number of access tunnels providing entry to the depot... initial indications indicate the target was engaged successfully," the MoD said.
There was no evidence of any civilian impact in the operation on Saturday evening and all the aircraft returned safely, the MoD added.
The British jets were backed up by a Voyager tanker plane.
Daesh - also known as the so-called Islamic State - imposed extremist governance over significant areas in Iraq and Syria before its territorial defeat in 2019.
"This operation underscores British leadership, and determination to stand shoulder to shoulder with our allies, to eliminate any resurgence of IS and their harmful and extremist ideologies in the area," the British Defence Secretary the Defence Secretary said.
British military aircraft have conducted patrols over Syria to "forestall any attempted resurgence" of the group subsequent to its defeat at the battle of Baghuz in the year 2019, the authorities noted.
"I must thank the personnel of the UK armed forces who took part in this strike for their professionalism and their courage," the Defence Secretary added. "Including them were thousands of UK service members deployed over Christmas and New Year. This action, to remove terrorist threats who threaten our safety, highlights how British military are ready to step up, continuously, keeping Britain secure at home and strong abroad."
In December, the American forces carried out what it called a "large-scale strike" against IS targets in the country, subsequent to an ambush claimed the lives of two US troops and a local interpreter in the Palmyra area.
The UN estimates Daesh still has roughly 5-7 thousand combatants in Iraq and Syria.